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doi: 10.1038/nrneurol.2016.111 105

by contrast, 4 g/d NR appeared to provide the best balance of yield and nutrient quality for optimal lactation

These characteristics restrict its functional efficacy, rendering less than 2% of curcumin bioavailable to the body and limiting its clinical use ( 8.1 Intestinal stability and permeability of curcumin Curcumins stability in the intestine is critical to its permeability and absorption