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The localized freezing can cause the same mechanical stress as freezer storage

It holds promise in various disease conditions, particularly in inflammatory bowel disease (IBD) treatment, where it has shown substantial efficacy and safety across multiple administration routes

The numerator thresholds were developed according to evidence and consensus-based clinical guidelines for ED time thresholds, including guidelines developed by The Joint Commission (TJC), the American College of Emergency Physicians (ACEP), and the Emergency Department Benchmarking Alliance as well as input from a TEP, literature reviews, and environmental scans

The SATURN study subsequently compared rosuvastatin 40 mg versus atorvastatin 80 mg and showed a similar magnitude of plaque regression with the two regimens (1.22% [1.52 to 0.90] vs 0.99% [1.19 to 0.63]