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Major depressive disorder, a frequent sequela of chronic stress, is likewise linked to CNSgut axis dysfunction and inflammatory activation [107,108,109]

The absorbance of the supernatant was measured spectrophotometrically at 412 nm

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Chemical modification of superoxide dismutase (SOD) with low molecular heparin [489], phospholipids [490, 491], mannosylation [492], or cationization [493] significantly extends its half-life and enables membrane-targeting ability