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It has been shown to signal natural repair processes, enhance collagen and elastin synthesis, and support dermal matrix remodeling

WeberM.TrampczynskaA.ClemensS.2006Comparative transcriptome analysis of toxic metal responses in Arabidopsis thaliana and the Cd( 2+ )-hypertolerant facultative metallophyte Arabidopsis halleri.950963,0140-7791 131

Animal models Three-month-old male PTP1B +/+ (wild-type) and PTP1B / mice on the C57Bl/6J 129Sv/J genetic background and maintained as described previously 41 were used throughout this study