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On the basis of the type of metal ion required as cofactor by SOD, various forms of the enzyme exist.23, 24 The metal ions which are normally bound by SOD are iron (Fe), zinc (Zn) copper (Cu) and manganese (Mn)

For instance, sustained non-oscillatory responses in macrophages promote chromatin remodeling and activate latent enhancers that regulate immune response genes

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Both oxidative stress and inflammatory reactions lead to medical problems associated with inflammation, and these chemicals are needed to reduce both (Figure 4)