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It has also been suggested that deafferentation of central auditory neurons due to loss of HCs and SGNs reduces leads to transneuronal degeneration, due to loss of neurotrophic support (e.g., Feng et al., Clues as to mechanisms of central auditory damage can also be inferred from research on the senescence-accelerated mouse model

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In addition, a lack of vitamin D in elderly individuals is associated with the pro-inflammatory phenotype of immune cells, which is likely to contribute to an increased risk of developing a serious infection

The reaction could not be explained by other variables such as location, season, or other medications taken at the same time