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We also describe the Bayesian implementation of our method, including adapting the proposed IPQ method within the MCMC algorithm and considering different bivariate covariance priors

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Conclusion Whilst severe B12 deficiency has a clear clinical picture with characteristic haematological and/or neurological features, establishing mild or borderline deficiency can be problematic as serum levels are maintained at the expense of tissue concentrations, and therefore serum levels of B12 may be in the low normal or borderline range despite a deficiency

This matches 12 ounces of 5% ABV beer, 5 ounces of 12% ABV wine, or 1.5 ounces of 40% ABV distilled spirits