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What are the effects of dupilumab on mast cells in patients with EoE

Washington (DC): National Academies Press (US)

doi: 10.1016/j.freeradbiomed.2015.10.420 61 ShearnCTSabaLMRoedeJROrlickyDJShearnAHPetersenDR

evaluated the pharmacodynamics, pharmacokinetics, safety, and tolerability of the single and multiple up-dose oral FPN inhibitor VIT-2763 in healthy volunteers and found that VIT-2763 has a safety profile similar to placebo and is well tolerated, with no serious adverse events and discontinuations due to adverse events