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Lipidomic results suggest that phosphatidylethanolamine (PE) containing arachidonic acid (AA) is the key membrane phospholipid for the occurrence of oxidation-driven ferroptosis ( System Xc- is a heterodimeric cell surface amino acid reverse transmitter

*Correspondence: Beata Kosmider [email protected] This article was submitted to Pulmonary Medicine, a section of the journal Frontiers in Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The pro-oxidative state can be induced by a disorganized lifestyle (inadequate diets, obesity, sleep restrictions, recurrent episodes of ketosis) or by the underlying condition (Kacarevic et al., 2020)

10.1126/science.1250808 Science 86 MurrD