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Here's what studies have consistently shown: Wrinkle Reduction and Skin Tightening Multiple double-blind clinical trials have demonstrated that GHK-Cu reduces the depth of fine lines and wrinkles, with improvements in the 3050% range after 12 weeks of consistent topical application in higher concentrations

He traced the effect to this small copper-binding peptide and launched five decades of research

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The results showed a significant increase in skin density and thickness, with a 67% reduction in wrinkle volume and improved elasticity, as measured by ultrasound and profilometry (Leyden et al., 2002)