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The Lock and Key Analogy Lets make it simple

LA has changed arrangement on its fatty acid-like skeleton, which allows it to capture the copper and iron ions, thereby forming a stable complex with these metals to achieve chelation of iron, copper, cobalt, manganese, zinc, cadmium, lead, nickel, arsenic, mercury and other transition metal ions [26, 62, 69,70,71]

The consequent oxidative stress resulting from metal exposure can also influence the lipid profile, with previous findings demonstrating that lead, mercury, iron, zinc, and arsenic affect dyslipidemia (measured via cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol) (Kim Dwon et al., 2022

That behavior favors inflammation, guarding, stiffness, and pain sensitivity