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Notably, knockdown of RFK in THLE-2 cells inhibited proliferation, while FADS knockdown had no effect on hepatocyte proliferation (Supplementary Fig

The key ferroptosis molecule GPX1 gene can also protect against memory impairments induced by A (142) by activating the cAMP response element-binding protein/brain-derived neurotrophic factor (CREB/BDNF) signaling pathway dependent on M1-mAChR (Shin et al., 2021)

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This intracellular ATP level is much higher in cancer than in normal cells due to heightened glucose uptake and glycolysis which is known as the Warburg effect [99]