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Redox Biol 84:103705

Studies have demonstrated that GA not only significantly reduces the levels of AST, ALT, TC, TG, and LDL-c induced by a high-fat diet (HFD), but also restores the levels of HDL-c, thereby playing a protective role for the liver

Notably, the SCFA effect on lost weight was abrogated in mice with adipose-specific disruption of PPAR, indicating that PPAR acted as a critical mediator of the beneficial effects of SCFAs in MetS (160)