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A.et al (2003)

doi: 10.1073/pnas.0704329104 318 FarahCMichelLYMBalligandJL

Sirtuin-1 activation controls tumor growth by impeding Th17 differentiation via STAT3 deacetylation

For a 10mg vial, adding 1mL of bacteriostatic water creates a 10mg/mL concentration that works well across the full dose escalation range from 2mg (20 units) to 8mg (80 units)