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forming bile salts, which play an important role in digestion

Activated glial cells can lead to oxidative stress, and excessive oxygen free radicals damage the cell membrane, mitochondria, and DNA, thus exacerbating the inflammatory response and even leading to neuronal damage and death

K.WinklerJ.WinnerB.GntherC.SP

(2016) reviewed the click chemistry approach to functionalize polymer NPs with sialic acid mimetics capable to express a high affinity for Siglec-3, counteracting the amyloid-beta protein deposition and plaque formation in the brain and, as a result, the Alzheimers disease progression