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Possible Complications When Diagnosed with Lumbar Spinal Stenosis Lumbar Spinal Stenosis (LSS) can lead to a range of complications, including: Chronic back and lower limb pain Decreased ability to exercise Reduced movement and function Muscle shrinkage Feelings of depression and anxiety due to these symptoms Lowered quality of life Cauda equina or conus medullaris syndrome, which are serious conditions that affect the nerves in the lower part of the spine There can also be problems related to open and less invasive treatments for LSS: Blood clot in the spine Tear in the outer layer of the spinal cord Infection at the surgical site Injuries to nerves or blood vessels caused by the surgery Items used to stop bleeding left in the body Instability in the spine New bone growth Failed back surgery syndrome, a chronic pain condition In rare cases, death can occur, reported in 0.5 to 2.3% of open laminectomy cases

These 5-kDa peptides with -helical structures are cationic and have high positive charge and isoelectric point (Neshani et al

These larger trials are designed to test a drugs efficacy in a patient population