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The careful selection of ligation sites Val25-Thr26 and Glu49-Ser50 helped maintain the hydrophobic balance and preserve biological activity

Collectively, these features underscore the unique biogenesis characteristics of PDEVs, shaped by plant-specific cellular organization and physiological context

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377 Iron overload, following increased intake, which may in particular result from the use of iron-containing implants widely employed in orthopaedic surgery, 378 or can occur after haemorrhagic stroke, results in compensatory upregulation of glial iron transporters, and down-regulation of neuronal iron transporters, both aimed at neuroprotection