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The concern is practical rather than safety-based: receptor desensitization, diminishing returns, and cost

Q2: Is AOD-9604 the same as HGH Fragment 176-191

A 24 h time point was chosen based on a previous report of using this time period for transfecting or treating 3T3-L1 cells with NNMT anti-sense oligonucleotides or a small molecule NNMT product inhibitor (1-MNA), respectively, for phenotypic measures