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Kazmi Z, Zeeshan S, Khan A, Malik S, Shehzad A, Seo EK, et al

Lipocalin-2 also protects against oxidative stress induced by excess free iron [96, 97]

Why Deficiency Matters Even mild deficiency can cause wide-ranging symptoms: Persistent fatigue or low energy Brain fog, mood changes, or poor concentration Tingling or numbness in hands and feet Pale skin or shortness of breath Reduced immune function These occur because B12 is critical for oxygen transport and nerve conduction