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Thus, the inability to account for inhibition of IGF-2 binding to the IGF-1R is an important limitation in this study, which should be considered when assessing outcomes from human trials using IGF-1R mAbs

Appl Environ Microbiol 80:76737682 Wang J, King JE, Goldrick M, Lowe M, Gertler FB, Roberts IS (2015) Lamellipodin is important for cell-to-cell spread and actin-based motility in Listeria monocytogenes