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Neuromol Med 21(1):111 Kumar D, Goel F, Rai SN (2025) The role of ABCA12 in neurodegenerative diseasesa review of molecular mechanisms and potential therapeutic implications

These physical symptoms occur because B12 deficiency damages nerve pathways throughout your entire body, not just your brain

It would likely involve establishing a baseline with each compound separately before attempting a very brief, low-dose combination phase to assess safety and tolerance