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doi: 10.3389/fbioe.2025.1668524 Received 18 July 2025 Revised 04 November 2025 Accepted 13 November 2025 Published 05 January 2026 Volume 13 - 2025 Edited by George Alexander Truskey, Duke University, United States Reviewed by Wagner Moneda Telini, Centro Universitrio de Votuporanga, Brazil Mai Abusalah, al-Ahliyya Amman University, Amman, Jordan, Jordan Updates Copyright 2026 Xiao, Li, Mu, Sun, Wang, Chen, Ma, Cao, Yang, Shao, Ding, Cui and Du

Low Ceruloplasmin levels may also be found in Menkes disease, malignancy, inflammatory bowel disease, thyroid disease, neonates, heterozygotes for WD and aceruloplasminemia Methods: Electronic medical record review Results: A 12-year-old Hispanic nonverbal autistic male with history of constipation and urticaria pigmentosa was referred for elevated serum transaminases with normal bilirubin levels