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These include hyperprolactinemia, thyroid disease, non-classical congenital adrenal hyperplasia (221, 222)

Wild-type zebrafish embryos serve as a robust system for investigating manganism 314 , while zebrafish carrying mutations in the slc30a10 , slc39a8 , and slc39a14 genes recapitulate many of the clinical phenotypes observed in humans 36,46,52