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Environmental Research , 248 , 118278

Without adequate cerebral folate, critical neurological processesincluding DNA synthesis, neurotransmitter production, and myelin formationare disrupted during crucial developmental windows

Genome breaks are exacerbated by poly (ADP-ribose) polymerase, leading to classic apoptotic phenotypes, including cell membrane vesiculation and apoptotic vesicle formation (71,72)