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SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells

Conversely, it has been reported that reducing PLD1 expression or inhibiting its enzymatic activity (loss of function) compromised the clearance of -syn aggregates (Bae et al., 2014)

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Diabetologia 52:10871091 Farfari S, Schulz V, Corkey B, Prentki M (2000) Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion