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VRK2 overexpression could suppress the increase of shrunken mitochondria and lipid ROS induced by TBHP, while BFA treatment abolished VRK2-mediated alterations (Fig

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Additionally, melatonin secretion patterns in NS workers were associated with differential methylation of key circadian genes, including RORA, MTNR1A, and PER3, suggesting a potential link between circadian disruption, epigenetic regulation, and cancer risk 196