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To investigate the metabolite profile of Down syndrome using the model, we began by increasing by 50% the V max of CBS, since the gene for CBS is on chromosome 21 and is expressed at 150% of normal

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[DOI] [PubMed] [Google Scholar] 87.Schwarzlander M., Fricker M.D., Muller C., Marty L., Brach T., Novak J., Sweetlove L.J., Hell R., Meyer A.J

The gut microbiota plays a crucial role in maintaining intestinal homeostasis, and disruptions in its composition and its metabolism can result in pathological damage to the intestines [5, 6]