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McMackin CJ et al

Xanthohumol is thought to destabilize c-Myc and promotes its ubiquitination as a consequence, resulting in the suppression of Akt/ flycogen synthase kinase-3 beta (GSK3) axis and inhibition of glioblastoma cell proliferation

Biotechnol Appl Biochem 180:426437 Kang SG, Zhou G, Yang P, Liu Y, Sun B, Huynh T et al (2012) Molecular mechanism of pancreatic tumor metastasis inhibition by Gd@ C82 (OH) 22 and its implication for de novo design of nanomedicine

For this goal, viruses and IBPs have to reprogram the host cell metabolism in a pathogen-specific manner to increase the supply of nutrients, energy, and metabolites which have to be provided to the pathogen to allow its replication