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gasseri : Lactobacillus gasseri IBD: Inflammatory bowel disease SCFAs: Short-chain fatty acids IL: Interleukin RCD: Regulated cell death ROS: Reactive oxygen species GPX4: Glutathione peroxidase 4 GSH: Glutathione System Xc: The cystine/glutamate antiporter system TCM: Traditional Chinese medicine DSS: Dextran sulfate sodium DAI: Disease activity index TNF-: Tumor necrosis factor- Lcn2: Lipocalin 2 FD-4: FITC-Dextran 4 Muc2: Mucin2 4-HNE: 4-Hydroxynonenal MDA: Malondialdehyde ACSL4: Acyl-CoA synthetase long-chain family member 4 FTH1: Ferritin heavy polypeptide 1 GSH: Glutathione KEGG: Kyoto Encyclopedia of Genes and Genomes MVA: Mevalonic acid IFN-: Interferon gamma PUFAs: Polyunsaturated fatty acids PGs: Prostaglandins References Feuerstein JD, Moss AC, Farraye FA

and use of definitions that may underestimate disease burden can restrict access to warranted systemic treatments [2,3,4,5, 8, 9]

There was limited density for the conjugated lipid, which could only be resolved in high-resolution receptor-focused maps of Cagri-AMY 1 R-G s and Cagri-CTR-G s structures, albeit modelling was restricted to the Glu linker and an adjacent short segment of the fatty diacid as the remainder of the modification was not resolved

Wang C, Sadovova N, Ali HK, et al