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Hedin CRH, Sonkoly E, Eberhardson M, Stahle M (2021) Inflammatory bowel disease and psoriasis: modernizing the multidisciplinary approach

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56-58 Not only is 15d-PGJ2 a potent Nrf2 agonist, that markedly increases cellular antioxidants, but it also has potent anti-inflammatory properties related to its capacity to S -alkylate several key cysteine residues in proteins regulating inflammatory pathways including NFkB and PPAR