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Extracellular Matrix and Connective Tissue Biology Healthy connective tissues rely on continuous remodeling of the extracellular matrix, coordinated cellular migration, and balanced communication between structural and immune cells

These electrophilic modulators mainly interact with C151 in KEAP1, thereby inhibiting NRF2 ubiquitination and increasing the activity of ARE-mediated antioxidant and detoxifying enzymes [280]

Acetoacetyl-CoA is then converted to 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA), followed by acetoacetate, and finally, -hydroxybutyrate (BHB) is supplied as a substrate for neuronal ATP synthesis

Abstract Considering that the fetal redox homeostasis is a key factor for normal prenatal development, this study researched the effects of maternal thrombophilia on fetal redox homeostasis by assessing the redox profile of amniotic fluid cells and amniotic fluid during the second trimester of pregnancy