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Heat dramatically increases the rate of hydrolysis

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doi: 10.1186/s41983-020-0159-7 152 ShiM.LiuC.CookT

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Synthetic small molecule SIRT1 activators Compared with natural products, synthetic SIRT1 activators offer several advantages, including defined molecular structures, high target selectivity, and stable pharmacokinetic profiles, making them a promising direction for the clinical application of SIRT1-targeted therapies

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