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J.ArizaA.FernandezJ.MorenoE.LagunaJ

To provide a more comprehensive exploration of the role of DNA methylation in neurodevelopmental disorders, we have also expanded the discussion on DNA methylation regulation in autism spectrum disorder (ASD) and intellectual disability (ID)

The reconstitution process is standard peptide preparation

Additionally, overexpression of alpha-synuclein increases the phosphorylation of NMDARs, thereby increasing the expression of NR1 and NR2B subunits and increasing the sensitivity of NMDARs to glutamate excitotoxicity (Yang et al., 2016)