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During cerebral ischemia, alterations in the bioelectric properties of neuronal cells occur, accompanied by the emergence of pathological slow waves

In such cases, the treatment strategies are likely to target systemic metastases, while the removal of metastatic LNs and targeting of non-metastatic draining LNs may potentially augment the effectiveness of immune checkpoint blockade (ICB) treatment ( Cancer metastasis in the lymphatic system Lymphangiogenesis in cancer Tumor growth stimulates both angiogenesis (6570), facilitating cancer metastasis through the blood circulation and lymphatic vasculature

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Cranwell WC, Lai VW, Photiou L, Meah N, Wall D, Rathnayake D, Joseph S, Chitreddy V, Gunatheesan S, Sindhu K, Sharma P, Green J, Eisman S, Yip L, Jones L, Sinclair R (2019) Treatment of alopecia areata: an Australian expert consensus statement