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Whole blood samples were collected into EDTA-coated tubes, and hematological parameters, including red blood cell count (RBC), hemoglobin (HGB), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) were measured using the automatic biochemical analyzer (Shenzhen Myriad Biomedical Electronics Co, China)

Complement complexes can be discovered in atherosclerotic lesions, and ECs exposed to complement are activated and improves the production of IL-6, IL-8 and MCP-1, thereby triggering the adhesion of monocytes to ECs 89

Likewise abnormalities in potassium channel have been reported in neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), a lethal neurodegenerative disease commonly called Lou Gehrigs disease 30 , and Parkinsons disease such that potassium channel blockers are part of treatment regimen in Parkinsons disease 31

Large-scale randomized controlled trials are urgently needed to establish safe lipid thresholds and optimize therapeutic strategies