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In a rat alkali-burn wound model, BPC-157 was associated with ERK1/2 activation and faster wound closure, along with increased proliferation and migration of endothelial cells in a parallel in vitro assay

[DOI] [PMC free article] [PubMed] [Google Scholar] 198.Inai T, Kitagawa N, Hatakeyama Y, Ikebe T, Iida H, Fujita M

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Platelet-rich plasma and mesenchymal stem cell therapies have the strongest evidence to date, showing moderate improvements in pain and function with generally favorable safety profiles, though long-term structural regeneration remains unproven