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Unfortunately, the first signs of Lyme disease are often overlooked

Tumours of the Liver

While many tumors harbor p53 loss-of-function mutations or deletions, others contain oncogenic gain-of-function mutations of p53 , resulting in the expression of mutant p53 protein in tumors, and such tumors often exhibit poor prognosis and aggressive tumor phenotypes (Muller and Vousden, 2013)