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Measurement of cellular iron Cell iron content assay kit (Solarbio, Beijing, China) was used to measure cellular iron contents based on assay contains hydroxylamine hydrochloride, which reduces Fe 3+ to Fe 2+ in cells, and under weak acid conditions, Fe 2+ and phenoline form a reddish-orange mixture, and the iron content can be calculated by measuring the OD value at 510 nm

People with kidney disease should avoid high-dose cyanocobalamin supplements specifically, as there is evidence it may accelerate kidney function decline

GraphPad Software, San Diego, USA) was used to create the figures

10.1007/s10495-018-1464-9 9 ChenJ.HuangC.WangJ.ZhouH.LuY.LouL.et al (2017)