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Conclusion This review synthesizes current evidence to summarize the therapeutic potential and underlying mechanisms of nanozymes in IMIDs, while highlighting key challenges and future directions to guide the development and clinical translation of nanozyme-based therapies

Hormonal Changes: Pregnancy : Hormonal changes during pregnancy can cause melasma or the mask of pregnancy leading to symmetrical dark patches on the face

To address this complex issue, researchers have explored diverse therapeutic strategies, including but not limited to remote ischemic preconditioning, remote ischemic postconditioning, and pharmacological interventions such as antioxidants, anti-inflammatory drugs, calcium channel blockers, as well as hypothermia treatment [30,31,32]

Maes M, Vandewoude M, Scharp S, De Clercq L, Stevens W, Lepoutre L, et al