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Researchers found that the participants had improved lean body mass and muscle strength, as well as decreased fat mass when compared to the placebo group

Adipose tissue isolation Epididymal white adipose tissue was isolated and minced with scissors

[0423] Other examples of immune modulators that can be attached to the anti- ALPP/ALPPL2 antibody include, but are not limited to, gancyclovier, etanercept, tacrolimus, sirolimus, voclosporin, cyclosporine, rapamycin, cyclophosphamide, azathioprine, mycophenolgate mofetil, methotrextrate, glucocorticoid and its analogs, cytokines, xanthines, stem cell growth factors, lymphotoxins, tumor necrosis factor (TNF), hematopoietic factors, interleukins (e.g., interleukin-1 (IL-1), IL-2, IL-3, IL-6, IL-10, IL-12, IL-18, and IL-21), colony stimulating factors (e.g., granulocyte-colony stimulating factor (G-CSF) and granulocyte macrophage-colony stimulating factor (GM-CSF)), interferons (e.g., interferons-alpha, interferon-beta, interferon-gamma), the stem cell growth factor designated " S 1 factor," erythropoietin and thrombopoietin, or a combination thereof

Antitumor activity was specially observed with 1.6 mg/kg Q2W and 2.0 mg/kg Q3W, with a remarkably lower proportion of AEs