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In dogs and cats with chronic gut disease, injectable B12 is often preferred over oral forms since damaged intestinal tissue cannot reliably absorb cobalamin taken by mouth

Firoozi said he would like to see a therapy developed using B12 for ulcerative colitis

In addition, in individuals whose neuropathies are attributed to vitamin deficiencies but do not improve/worsen despite sufficient supplementation, alternative causes should be considered, including POEMS syndrome