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42,43 Cholesterol-enriched lipid droplet formation in podocytes, combined with dysregulated insulin signaling and hyperglycemia, exacerbates podocyte death and detachment

[DOI] [PubMed] [Google Scholar] 2.Yang Y., Shi Y

Stem Cells, 33 (3), 627638

Mitochondrial DNA (mtDNA) depletion and mutations in certain mitochondrial genes are linked to reduced insulin secretion and increased oxidative stress, although studies on the exact mechanisms are scarce ( 2.4.1 Basic science research Similarly, in the context of PD, mitochondrial dysfunction can drive neurodegeneration