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As part of the PDH complex, PDHB participates in the decarboxylation of pyruvate and is involved in the glycolytic pathway, thereby modulating cellular energy metabolism

NAC is able to reduce cysteine conjugates and has the potential to act as an anticancer agent, however, caution should be paid since NAC has been reported to enhance the metastatic potential of melanoma cells in mice (Piskounova et al