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A 2021 review performed by the nonprofit organization Association for Science in Autism Treatment found that the Brain Balance approach lacks sufficient empirical evidence and should therefore be considered a pseudoscientific treatment. The current program is based on contemporary developmental neuroscience and supported by a modern evidence base developed independently of any former contributors, a Brain Balance representative told The Transmitter

She also explains how to align your work and relationships of all kinds with your true self and how to embrace the discomfort and process of leaving unhealthy relationships

Also, a decrease in the level of choline, the precursor of the neurotransmitter ACh and the agonist for nicotinic-cholinergic receptor (nAChR), was determined in individuals diagnosed with ASD (Friedman et al., 2006), with the severity of ASD related to the decreased level of cytosolic ACh (Sokol et al., 2002)