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A 14-day continuous course was well-tolerated and effective in human trials [2]

The medium was changed every 3 days, and recombinant GDF11 (10 ng/ ml) was added on the first day of culture

Studies investigating subpopulations within brain regions (i.e., input regions, cell types, projection targets) have utilized many techniques, including targeted expression of optogenetic tools, tracing strategies, and reporter animal models

This differential response enhances the therapeutic potential of hyperthermic treatment when combined with Goralatide, as it selectively protects normal cells from heat-induced damage while leaving leukemic cells highly susceptible