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Autophagy (2020) 16(11):206983

Notably, trans-Chalcone also decreased nuclear factor B (NF-B) activation and the mRNA expression of inflammasome components such as ASC, NLRP3, pro-IL-1 and pro-caspase-1 (74)

These results indicate that red blood cells can signicantly affect the extracellular pool of glutathione, participating in cooperation with the liver and other tissues in the synthesis and metabolism of GSH