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Patients should be aware that tirzepatide may reduce the effectiveness of oral contraceptives, particularly after initiation and dose increases

[2] This pharmacokinetic profile affords convenient once-monthly dosing schedules that many patients and practitioners find advantageous, while the use of grapeseed oil may reduce the likelihood of local irritation associated with heavier oils historically used in parenteral hormone products

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Emerging animal studies also point to possible joint and cartilage benefits, particularly when paired with hyaluronic acid therapy