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Description

Since LB nucleation requires attractive interactions, our findings suggest that C-terminal truncated Syn variants may initiate the nucleation process

Iron chelators, including deferoxamine (DFO), deferasirox (DFX), and deferiprone, are clinically approved for the management of iron overload disorders and have recently been repurposed as inhibitors of ferroptosis

Front Microbiol 11:610173

These residues are also actively modified by post-translational regulation, including disulfide formation and S-nitrosylation (Paulsen and Carroll, 2013