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The expression of CDO under these conditions could play an important role in altering the local redox environment

To further explore the specific roles of GPX3 and MYC in the immune microenvironment, we performed single-cell sequencing-based ferroptosis scoring of different immune cell populations in RA patients, particularly focusing on communication differences between high and low ferroptosis-scoring CD8+ T-cell subpopulations and other immune cells

In in vitro studies, ivosidenib has been shown to inhibit mutant IDH1 at significantly lower concentrations than it does the wild-type enzyme