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J Membr Biol 252(45):273292
There are also conditions where IV therapy is often still possible, but only after consultation with a physician to adjust formulation, volume, or infusion rate: Heart or circulation issues , such as controlled congestive heart failure, uncontrolled high blood pressure, or a history of blood clots Kidney conditions , including chronic kidney disease, reduced kidney function, or patients currently on dialysis Electrolyte imbalances , such as elevated potassium, sodium, or calcium levels Prescription medications that may interact with IV fluids, vitamins, or minerals Pregnancy and breastfeeding also fall into this category
475 Aberrant and premature developmental gliogenesis (which ultimately affects both neurones and glia) lies at the core of the cellular pathophysiology of Down syndrome
As a demonstration of this, cultured rat hippocampal neuronal cells were protected from oxidative stress with uric acid [38], and administration of uric acid 24 hours prior to middle artery occlusion also attenuated brain injury induced by acute ischemia in rats [38]
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